A key cold medicine ingredient is basically worthless

A picture of shelves containing cold medications on a store shelf, with price tags hanging on the bottom of the shelves. Cold medications on a shelf pictured in Miami, Florida, on September 12th, 2023. | Photo by Joe Raedle / Getty Images

The FDA’s 16-member advisory panel unanimously voted yesterday that oral phenylephrine, a common active ingredient in cold medications, is no better than a placebo for treating congestion. The call by the panel sets up potential FDA action that could force the removal of certain over-the-counter medications containing the ingredient — including certain formulations of Mucinex, Sudafed, Tylenol, and NyQuil — from store shelves.

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